Dynamics of Renal Fibrosis Markers on the Basis of Complex Treatment in Chronic Heart Failure with Anemia

Tosheva Khakima Bekmurodovna, Gadaev Abdigaffar Gadaevich

doi:10.17762/pae.v58i3.3861

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Published: Mar 15, 2021

DOI: https://doi.org/10.17762/pae.v58i3.3861

Tosheva Khakima Bekmurodovna, Gadaev Abdigaffar Gadaevich

Abstract

Renal fibrosis markers were evaluated in dynamics to study specific changes in the kidneys of patients with different hemodynamic types and functional classes of chronic heart failure with anemia and to evaluate the effectiveness of complex treatment. The renal fibrosis marker TGF-β₁ in the blood was 2591.0 ± 108.4 and 755.0 ± 18.87 pg / ml, respectively, in the absence of chronic heart failure and anemia (p˂0.001). This was indicative of a fibrosis process occurring in the kidney. After complex treatment with iron supplements, the TGF-β₁ index decreased by 2.25 times (p (0.001), the clinical condition, quality of life and endurance to physical activity changed significantly positively.

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Vol. 58 No. 3 (2021): Volume 58 No. 3 (2021)

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